The Cataracs by The Cataracs free essay sample

The Cataracs The Cataracs is a two-man group who does both pop and hip-hop music. Their message is about their lives and sometimes their partying. Most of their music is soothing and they make different songs of different types. Some of their songs include rap and some are just singing. One of their songs called â€Å"Baby Baby† describes their love and is them singing. Another one of their songs, â€Å"2nite†, talks about all the things the do on their free time. Their newest song, â€Å"Top Of The World†, describes their relationships. Their songs have many different messages and describe real-life. Their newest album, â€Å"Song We Sung In Showers†, is smoother and less hardcore than their first album. Their first album, â€Å"Technohop Vol. 1†, is filled with more rap songs than their newest album. So far, they have four albums and one coming out this year. The Cataracs are a free group and their songs fall under different genres. We will write a custom essay sample on The Cataracs by The Cataracs or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page

Centromere Location and Chromosome Separation

Centromere Location and Chromosome Separation A centromere is a region on a chromosome that joins sister chromatids. Sister chromatids are double-stranded, replicated chromosomes that form during cell division. The primary function of the centromere is to serve as a place of attachment for spindle fibers  during cell division. The spindle apparatus elongates cells and separates chromosomes  to ensure that each new daughter cell has the correct number of chromosomes at the completion of mitosis and meiosis. The DNA in the centromere region of a chromosome is composed of tightly packed chromatin known as heterochromatin. Heterochromatin is very condensed and is therefore not transcribed. Due to its heterochromatin composition, the centromere region stains more darkly with dyes than the other regions of a chromosome. Key Takeaways Centromeres are regions on a chromosome that join sister chromatids whose primary function is for the attachment of spindle fibers in cell division.While centromeres are typically located in the central area of a chromosome, they can also be located near the mid-region or at a number of different positions on the chromosome.Specialized zones on centromeres called kinetochores attach the chromosomes to spindle fibers in prophase in mitosis.Kinetochores have protein complexes that generate kinetochore fibers. These fibers help to orient and separate chromosomes during cell division.In meiosis, in metaphase I, the centromeres of homologous chromosomes are oriented toward opposite cell poles while in meiosis II, spindle fibers extending from both cell poles attach to sister chromatids at their centromeres. Centromere Location A centromere is not always located in the central area of a chromosome. A chromosome is comprised of a short arm region (p arm) and a long arm region (q arm) that are connected by a centromere region. Centromeres may be located near the mid-region of a chromosome or at a number of positions along the chromosome. ​ Metacentric centromeres are located near the chromosome center.Submetacentric centromeres are non-centrally located so that one arm is longer than the other.Acrocentric centromeres are located near the end of a chromosome.Telocentric centromeres are found at the end or telomere region of a chromosome. The position of the centromere is readily observable in a human karyotype of homologous chromosomes. Chromosome 1 is an example of a metacentric centromere, chromosome 5 is an example of a submetacentric centromere, and chromosome 13 is an example of an acrocentric centromere. Chromosome Segregation in Mitosis Prior to the start of mitosis, the cell enters a stage known as interphase where it replicates its DNA in preparation for cell division. Sister chromatids are formed that are joined at their centromeres.In prophase of mitosis, specialized regions on centromeres called kinetochores attach chromosomes to spindle polar fibers. Kinetochores are composed of a number of protein complexes that generate kinetochore fibers, which attach to spindle fibers. These fibers help to manipulate and separate chromosomes during cell division.During metaphase, chromosomes are held at the metaphase plate by the equal forces of the polar fibers pushing on the centromeres.During anaphase, paired centromeres in each distinct chromosome begin to move apart as daughter chromosomes are pulled centromere first toward opposite ends of the cell.During telophase, newly formed nuclei enclose separated daughter chromosomes. After cytokinesis (division of the cytoplasm), two distinct daughter cells are formed. Chromosome Segregation in Meiosis In meiosis, a cell goes through two stages of the dividing process. These stages are meiosis I and meiosis II. During metaphase I, the centromeres of homologous chromosomes are oriented toward opposite cell poles. This means that homologous chromosomes will attach at their centromere regions to spindle fibers extending from only one of the two cell poles.When spindle fibers shorten during anaphase I, homologous chromosomes are pulled toward opposite cell poles but sister chromatids remain together.In meiosis II, spindle fibers extending from both cell poles attach to sister chromatids at their centromeres. Sister chromatids are separated in anaphase II when spindle fibers pull them toward opposite poles. Meiosis results in the division, separation, and distribution of chromosomes among four new daughter cells. Each cell is haploid, containing only half the number of chromosomes as the original cell. Centromere Anomalies Centromeres play an important role by participating in the separation process for chromosomes. Their structure however, can make them possible sites for chromosome rearrangements. Keeping the integrity of centromeres intact is thus an important job for the cell. Centromere anomalies have been linked to various diseases like cancer.

All About Zero

All About Zero All About Zero All About Zero By Mark Nichol Zero is the basis of a small set of terms and idiomatic phrases, which are listed and defined below. Zero derives, through French and Italian, from the Latin term zephirum, which in turn stems, as do the other mathematical terms algebra and algorithm, from Arabic: Sifr means â€Å"cipher† (and is the origin of that word as well). Sifr, in turn, comes from Sanskrit. Absolute zero (quantified as 273.15 degrees below zero Celsius) is the temperature at which matter stops moving, while ground zero is the origin point of a phenomenon. (Originally, it referred to the blast site of a thermonuclear explosion.) Zero hour is the time at which something is scheduled to begin. Zero gravity and zero visibility refer to a near, not absolute, absence of the qualities referred to in the phrases, and patient zero is the first person to contract a disease in an outbreak. The colloquial expression â€Å"From zero to hero† denotes a change in state from anonymity or a lack of distinction or popularity to fame, from the sense of zero as meaning â€Å"an undistinguished or worthless person.† (One can also, unfortunately, transition in the other direction as well.) To zero in is to focus on something or to come closer to it; the expression stems from the idea of adjusting a setting on a device or instrument to zero but originally applied to shooting a firearm. To zero out is unrelated- it means either to reset something, such as timer, or to cut off funding or reduce a quantity. Zero tolerance is the concept of absolute adherence to a rule; the phrase has entered mainstream discourse in references to zero tolerance for weapons or illegal drugs in a given area or jurisdiction. A zero-sum game, meanwhile, is a situation in which a defeated competitor or participant loses as much as the victor wins. (The sum of the gains and losses is zero, hence the name.) Want to improve your English in five minutes a day? Get a subscription and start receiving our writing tips and exercises daily! Keep learning! Browse the Expressions category, check our popular posts, or choose a related post below:How to Format a US Business LetterRules for Capitalization in Titles50 Synonyms for â€Å"Villain†

Research Paper Example | Topics and Well Written Essays - 1000 words - 2

Research Paper Example Moreover, the article elaborates on the several facets of evolution. This includes the notion that all living species share a common ancestry. Consequently, the theory states that there exists a relation among the entire world’s species. The second facet pertains to the process of natural selection that drives evolution. Evidently, the natural selection process is also known as the survival of the fittest. Thus, the author offers an explanation of survival of the fittest theory or the natural selection process. Evidently, the theory was formulated by Darwin who believed that all species struggled to fight for limited resources. However, Darwin theorized that each individual species possessed a difference in gene superiority that exhibited greater survival chances. "What is Evolution?"Â  Science – AllAboutScience.org. allaboutscience.org, n.d. Web. 27 Nov. 2012. . The article begins by delving into the definition of evolution. To this end, it defines evolution as a syst ematic process whereby an organism undergoes change into a more complex and enhanced form. Moreover, the article acknowledges that the evolution theory has been used to explain life on earth. In addition, the article elaborates on the various components of evolution. ... In reference to micro evolution, the article stipulates that there are variations that occur within a species. For example, micro evolution is used to explain how wolves, foxes, dogs, coyotes, jackals and dingoes evolved from a parent pair of dogs. Incidentally, the variations occur in a downward manner and are limited by genetic codes. This means that species such as dogs do not develop new limbs such as wings and change to flying. To this end, there is neither loss in genetic information nor any further addition. On the other hand, macro evolution relates to the important or greater changes in the primary functions by organisms. Moreover, macro evolution involves change from a particular kind of animal or plant into another. In addition, it occurs after several genetic mutations as opposed to during the life of a single organism. Thus, macro evolution attempts to offer an explanation of how the millions of different species came into existence. Kim, Seongcheol, Pudur Jagadeeswaran, Vrinda Kulkarni, and Maira Carrillo. "PLOS ONE: Evolution of Primary Hemostasis in Early Vertebrates."Â  PLOS ONE: Accelerating the Publication of Peer-Reviewed Science. PLoS ONE, 1 Jan. 2009. Web. 27 Nov. 2012. http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0008403. The primary research article delves into the evolution of primary hemostasis in early vertebrates. To this end, the authors define hemostasis as a defensive system that protects an organism by stopping bleeding when an injury occurs. Evidently, the researchers discovered that the main hemostatic factors in mammals were present in the early vertebrates. Moreover, they acknowledged that the exposure of the vascularised

Editorial Essay on Rafael Correa (President of Ecuador) - 1

Editorial on Rafael Correa (President of Ecuador) - Essay Example Of course, this is not a view that is held by all and a number of organizations and people inside and outside the republic have referred to him as an autocrat and a guile politician. However, the evidence speaks for itself, and it cannot be denied that the nation is doing better place than it was before the Rafael Correa came into power. His achievements cannot be downplayed, and it is doubtful that his rivals would have been able to do the same had they been given the chance to take his position. Rafael Correa is an economist that was educated in three different countries namely his homeland Ecuador, the United States and Belgium (Ghosh, 2012). He has used this education to improve the financial status of his country through a number of economic policies that he has implemented over the years. One of the most controversial moves with regard to these policies has been his declaration of Ecuador’s national debt as illegitimate on the basis that it was contracted by previous regimes that were despotic and corrupt with no regard for the country thus making the debts odious in nature. This move caused waves in the international community as it meant that the country planned to default on over 3 billion dollars worth of debt (Enrico, 2009). The president fought his opposition on this subject in the international courts and eventually managed to reduce the price of the outstanding bonds by over 60%, which was an amazing result (Enrico, 2009). Correa has also managed to win over the hearts of his people through his achievements, and concern for Ecuador’s welfare and as a result has been elected twice into office. One of his main non-political controversies includes his relationship with the media which can be said to be strained at best as a number of critics have accused him of interfering with their independence. Over the past years, he has taken a number of journalists and media

Treating diabetic foot ulcers

Treating diabetic foot ulcers The aspect of professional practice I choose related to my role as an adult nurse was diabetic foot ulcers. I choose this topic because it is often seen and treated by nurses and so understanding the treatments available and the effect living with diabetic foot ulcers has on individuals in very important. The first article I am going to discuss and evaluate is the ‘short report: the effect of topical phenytoin in healing diabetic foot ulcers: a randomised control trial’. This was located from the Diabetes UK website. This article explores how the use of a topical treatment for treating diabetic foot ulcers may be more conducive for the healing process as it contradicts the need for medical intervention as well as minimising patient caused to the individual. This study concludes that there were no changes in the diabetic foot ulcers being assessed between the two trail groups. This implies that the study doesn’t support the use of phenytoin in the treatment of diabetic foot ulcers. In relation to the hierarchy of evidence, this article falls under randomized controlled trials, which is the second from the top on the hierarchy. The National Institute for Clinical Excellence (NICE) defines a randomized control study as ‘A study in which a number of similar people are randomly assigned to two (or more) groups to test a specific drug or treatment. One group (the experimental group) receives the treatment being tested; the other (the comparison orcontrol group) receives an alternative treatment, a dummy treatment (placebo) or no treatment at all. The groups are followed up to see how effective theexperimental treatmentwas. Outcomesare measured at specific times and any difference in response between the groups is assessed statistically. This method is also used to reducebias.’ (NICE 2013). According to the British Medical Journal (BMJ), randomised controlled trails are the most thorough and precise technique of assessing if the participant is reacting p ositively to the treatment they have been administered. This also contributes towards managing the monetary value of the study and its effectiveness. The BMJ states that this method of evidence can come with some ethical issues one being, ‘exposing patients to intervention believed to be inferior to current treatment.’ (1998). They also express that although not all studies conducted by this means may be unethical, the validity of using this method may be unreliable, one of the main reason for this is due to the struggle to get the population to sign up to be a participant in the trail. In a case study directed by Wootton R. (2000), it can be argued that although treatment offered in RCTs may be inferior to current treatment, it can work for the benefit of the participant and when it does the results are more desirable than what was seen from current treatment. The second article I am going to discuss and evaluate is ‘debridement of diabetic foot ulcers’. This article was located in the Cochrane library. This article studies the debridement of foot ulcers and what impact it has on healing the diabetic foot ulcer. It also explores the use of dressings on the wound and what dressings apart from the standard gauze had a positive impact on the healing process. The findings of this study showed that the dressing that was being trailed had a positive impact on healing DFU and in an increased time compared to the standard gauze. From this article it Is clear that debridement as well as the other dressing which was trailed has a profound effect on the healing of DFU’s which may have a direct impact on the variations of dressings nurses have to treat diabetic patients. In accordance to the hierarchy of evidence, this article is a systematic review which comes at the very top of the hierarchy. The Cochrane Collaboration agree syst ematic reviews are the most reliable if they are carried out correctly because ‘Researchers conducting systematic reviews use explicit methods aimed at minimizing bias, in order to produce more reliable findings that can be used to inform decision making.’ (2013). This definition has been demonstarted in the article which has been chosen as they have managed to keep to the strict methods used to eliminate bias. One of them being randomised controlled trails. This type of trial ensures that all participants are randomly put in control groups where they would receive a placebo or the actual drug. This trail is strictly confidential as only those people conducting the study not assisting know which group is receiving what drug. All results obtained from the trail are ‘assessed by rigorous comparison of rates of disease, death, recovery, or other appropriate outcome in the study and control groups.’ (The Centre For Evidence Based Medicine. 2013). Leibovici L an d Reeves D also hold systematic review in high esteem describing it as a ‘powerful tool deployed in the pursuit of evidence based practice.’ (2005). They argue that systematic reviews do not just focus on the drug or treatment in question but highlight questions which are important to patients from the point of view that the patients well -being is the primary outcome of the study. Whereas in some clinical trails the primary outcome would reflect the need to save resources or to attempt to claim that certain treatments have an advantage which isn’t always the case. Despite systematic reviews appearing to cover all areas, some researchers have conflicting views on the expenses involved to run a study using individual patient data (IPD). According to Stern and Simmes (1997) IPD is much more expensive and time consuming than other research methods. However it is argued that due to the advancement of technology obtaining patient data is not as time consuming or expensive than in the 90’s. The final article I am going to discuss and evaluate is â€Å"Whatever I do is a lost cause.’ The emotional and behavioural experiences of individuals who are ulcer free living with the threat of developing further diabetic foot ulcers’. I obtained this article from the online Wiley Library. The article is relevant to my discipline as nurses treat many patients who currently have or have had diabetic foot ulcers in the past. This article gives and in depth picture of the fears of those who have had successful treatment for their DFU but are afraid of them returning. This article homes in on the feelings of the patients and how different aspects of DFU and the possible consequences affect their lives and how they approach the condition. However it doesn’t acknowledge how beneficial the treatments they received were. And the effects it had on them emotionally and physically if any. This article is qualitative study which according to the hierarchy comes at the bottom under the heading expert opinion. The Office of National Statistics use Ritchie and Lewis (2003) definition of qualitative study which is, ‘a naturalistic, interpretative approach concerned with understanding the meanings which people attach to actions, decisions, beliefs, values and the like within their social world, and understanding the mental mapping process that respondents use to make sense of and interpret the world around them’. The National office for statistics continues on the say that qualitative research offers an extended understanding of the subject and information related to it. Moreover it explains reasons for certain findings, evaluate how effective the study was and how it would aid their research. According to Ewe Flick the need for qualitative research has increased in the last few decades due to the rapid changes of society. He refers to it as a means to keep up to date with the current situations. Although qualitative research has been a fundamental study for the past couple decades, there are many defects in this method. Becker and Geer (1960) highlighted the fact that although the interviewer and participant speak the same language, there may be some discrepancies with the interpretation, which in effect may leave the interviewer without information he needs/ wanted. According to Beaker and Geer another reason it may be difficult for the participant to open up about certain issues which are bought up. This again may be another factor which prevents the researcher getting all the information they need. There also positives to this research method. Qualitative research is also known as going out on the field because the researcher has to find the participants and in some ca ses has to meet in an environment that suits them. The advantage of this is that if a participant who is being interviewed about a sensitive subject is in the comfort of their own home then they may feel more able to talk about the issues raised as Crabtree and Miller (1991) suggested. References Leibovici L Reeves D. (2005) Systematic reviews and meta- analysis. Journal of antimicrobial chemotherapy. Page 803. Volume 56. The Cochrane Library. (2013) http://www.thecochranelibrary.com/view/0/AboutCochraneSystematicReviews.html Last accessed 12th January 2014 Sage Publications (2002) http://ehp.sagepub.com/content/25/1/76.full.pdf+html Last accessed 11th Janurary 2014 Flick U. (2009). Introduction to Qualitative Research. 4th edition. London. Sage Publications Office for National Statistics- http://www.ons.gov.uk/ons/guide-method/method-quality/general-methodology/data-collection-methodology/what-is-qualitative-research-/index.html last accessed 12th January 2014 National Institute for Health and Care Excellence (2011) http://www.nice.org.uk/website/glossary/glossary.jsp?alpha=R Last accessed 12th January 2014 British Medical Journal (1998) http://www.bmj.com/content/316/7126/201 Last accessed 12th January 2014 British medical Journal (2000) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC27370/ Last accessed 12th January 2014

The Beaux-Arts Style

The beaux-arts style of architecture dominate the architecture of public buildings from 1890 to 1920 because the style was first popularized during the well attended Columbian Exposition of 1893. This style was to be emulated by many entities far and wide. The term â€Å"Beaux Arts† refers to the com/music-appreciation-final/">American Renaissance period from about 1890 to 1920 and encompasses the French Renaissance, the Italian Renaissance, and the neoclassical Revivals.In addition, most of the leading American architects of that period had been academically trained many of whom had trained at Ecole des Beaux Arts in Paris.These facts, together with the fact that America was emerging as a dynamic industrially powerful nation and was becoming a world power at the same time, were proof that America had arrived. Added together, these facts pushed the citizens of the nation to desire architectural proofs of their aspirations and desire to prove to the word that America was a cult ural and political equal to any nation in the world. The Beaux-Arts style is extravagant reflecting the attitude and taste of the industrial barons of this pre-tax era. Their homes were flamboyant and theatrical reflecting a desire to flaunt their wealth.The Beaux-Arts style fits this desire precisely. These industrialists gave commissions to these architects to build their sumptuous residencies in fashionable neighborhoods and exclusive summer enclaves. These grand houses reflected the desire for â€Å"conspicuous consumption. † This spirit of grandeur prompted many cities to erect grand public buildings as well. Every city aspired to outdo its neighbor. The American dream was to emulate the lead of the industrialists and proclaim their wealth and solidity. Public libraries, train stations, town halls, courthouses, office buildings, even prisons manifested this grandeur.Because this style is classical in nature but grand in scale, the buildings are more extravagant. This sty le is theatrical. Elaborate moldings, pilasters, wreaths, garlands, festoons, dentils, cartouches and figure sculpture all are a part of this style. This proclaims to the world power and wealth. Exactly what the era was about. This reflected what the nation’s psyche was about during this period. Bold, new, powerful, and wealthy. This nation was finally a force to be reckoned with. No longer a colonial appendage, but a country equal to any and all.